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Guide to the Philip Handler papers, 1933 - 1982 (MC.0015)

Abstract

Professor (1939-1984) and chair (1949-1969) of the Department of Biochemistry at Duke University.

Contains correspondence, notices, committee files, calendars, agendas, reports, writings, clippings, programs, speeches, text of speeches, tributes, biographical materials, and photographs. Major correspondents include Wilburt Cornell Davison, and Barnes Woodhall. Also contains some correspondence between William A. Perlzweig and other medical professionals. Major subjects include Duke University's Research Training Program, Cold Spring Harbor Laboratories, medical education, National Academy of Sciences, Lederle Laboratories, and Oak Ridge Laboratories.

Descriptive Summary

Call Number
MC.0015
Title
Philip Handler Papers
Date
1932-1982
Creator
Handler, Philip
Extent
20.00 linear feet
Repository
Duke University Medical Center Archives

Collection Overview

Organized into the following series: Professional Correspondence, 1933-1982; Biographical Materials and Memoirs, 1961-1982.

13 record storage boxes

Restrictions on Access & Use

Some collections are stored off site and must be requested at least 48 business hours in advance for retrieval.

Access Restrictions

Some folders may be restricted due to the presence of personal health information. Contact the Archivist for information about access.

Use Restrictions

Copyright for Official University records is held by Duke University; all other copyright is retained by the authors of items in these papers, or their descendants, as stipulated by United States copyright law.

Contents of the Collection

1. Professional Correspondence, 1933-1982

Scope and Contents note: Contains professional correspondence between Handler and colleagues at National Academy of Sciences, Lederle Laboratories, various foundations, and universities. Duke University correspondence includes materials pertaining to the Dept. of Biochemistry, Cold Spring Harbor Laboratories, Oak Ridge Laboratories and local disaster response planning, chair search committees, and the Research Training Program. Major correspondents include Wilburt Cornell Davison and Barnes Woodhall. Also contains some correspondence between William A. Perlzweig, (chair of the Dept. of Biochemistry from 1930 to 1949) and colleagues dated from 1934 to 1955.

Baird - Atomic, Inc., 1960
Box 1
Ted Bates (nutrition of bread), folder 1, 1959
Box 1
Ted Bates (nutrition of bread), folder 2, 1959
Box 1
Beaufort, N.C. Laboratory, 1963-1963
Box 1
J.T. Edsall, 1962-1963
Box 1
Environmental Health Center (correspondence to President Kennedy), 1963
Box 1
Goldblatt, Harry, 1951
Box 1
Gordon Research conferences, 1965
Box 1
Greenstein Memorial Foundation, 1961
Box 1
Paul M Gross Symposium, 1964-1965
Box 1
Gyorgy, Paul, 1944-1949
Box 1
Hartwick College, 1966
Box 1
Hawaii, Univ. of, 1961
Box 1
Holt, L.E. to William A. Perlzweig, 1943-1944
Box 1
Indiana University, Tracy Sonneborn, 1963-1964
Box 1
Institute for Defense Analyses, 1961-1967
Box 1
Institute of General Medical Sciences, National Institutes of Health (includes correspondence with Lister Hill, senator), 1961
Box 1
Institute on Man and Science, Hawaii, 1965-1966
Box 1
Hebrew University of Jerusalem, 1960-1966
Box 1
Kearney, Edna B., 1964
Box 1
Kettering Institute, 1962-1963
Box 1
Klein, J. Raymond, 1935-1947
Box 1
Kohn, Henry I., 1948-1953
Box 1
Kondritzer, A.A. to William A. Perlzweig, 1934-1941
Box 1
Korkes, Seymou, 1953-1957
Box 1
Lederle Laboraties (includes correspondence with William A. Perlzweig), 1933-1955
Box 1
Life Insurance Medical Research Fund, 1945-1958
Box 1
Institute of Life Insurance, 1951
Box 1
Macy, Josiah, Jr. Foundation, 1948-1952
Box 1
Markle Foundation, 1940-1961
Box 2
Marx, Walter to William A. Perlzweig, 1937-1940
Box 2
Mead Johnson Laboratories, 1962-1965
Box 2
Meek, Geoffrey, 1961-1962
Box 2
MEND (manuals for handling mass disaster casualties at Duke Hospital), 1958-1959
Box 2
Merck and Co., 1942-1961
Box 2
Mommaerts, W.F.H.M., 1953-1957
Box 2
Some Major Issues Concerning the Support of Fundamental Research and Graduate Education in Science, (with comments by Douglas M. Knight and R. Taylor Cole), 1967
Box 2
American Association for the Advancement of Science, 1967
Box 2
American Council on Education, 1963
Box 2
Amos, Bernard, 1961-1962
Box 2
American Society of Biological Chemists, undated
Box 2
Council Correspondence, 1958-1960
Box 2
Committee on Plans for Scientific Meetings, 1962-1963
Box 2
ASBC Council, 1958-1963
Box 2
President's File, folder 1, 1962-1963
Box 2
President's File, folder 2, 1962-1963
Box 2
Fifth International Congress of Biochemistry, 1961
Box 2
National Academy of Sciences calendars and agendas, folder 1, 1980-1982
Box 2
National Academy of Sciences calendars and agendas, folder 2, 1980-1982
Box 2
National Academy of Sciences calendars and agendas, folder 3, 1980-1982
Box 2
National Academy of Sciences calendars and agendas, folder 4, 1980-1982
Box 2
National Academy of Sciences calendars and agendas, folder 5, 1980-1982
Box 2
National Academy of Sciences calendars and agendas, folder 6, 1980-1982
Box 2
National Academy of Sciences calendars and agendas, folder 7, 1980-1982
Box 2
National Academy of Sciences calendars and agendas, folder 8, 1980-1982
Box 2
National Academy of Sciences calendars and agendas, folder 9, 1980-1982
Box 2
National Academy of Sciences calendars and agendas, folder 10, 1980-1982
Box 2
National Academy of Sciences calendars and agendas, folder 11, 1980-1982
Box 2
National Academy of Sciences calendars and agendas, folder 12, 1980-1982
Box 2
National Academy of Sciences calendars and agendas, folder 13, 1980-1982
Box 2
National Academy of Sciences calendars and agendas, folder 14, 1980-1982
Box 2
National Academy of Sciences calendars and agendas, folder 15, 1980-1982
Box 3
National Academy of Sciences calendars and agendas, folder 16, 1980-1982
Box 3
Long-Range Planning Committee, 1958-1959
Box 3
Planning and Development Committee, 1958-1959
Box 3
Committee on Deanship, 1959-1960
Box 3
Committee on Pharmacology chair, 1959-1960
Box 3
Committee on Psychology chair, 1960-1969
Box 3
Committee on Radiological Safety, 1951-1962
Box 3
Radioisotopes Committee of the United States Atomic Energy Commission, Division of Licensing Isotopes Branch, 1951-1961
Box 3
Woodhall, Barnes, 1960-1964
Box 3
Cold Spring Harbor Laboratories, 1962-1964
Box 3
Cold Spring Harbor Laboratories, 1964-1967
Box 3
Duke-Medical Scientists Program, 1967-1969
Box 3
Oak Ridge Laboratories, 1965-1966
Box 3
FASEB Advisory Committee Agenda, 1964-1965
Box 3
FASEB American Biological Council, 1964-1968
Box 3
Gerontology Society, 1961-1969
Box 3
Health Manpower Report, 1967
Box 3
Hollaender, Alexander (Oak Ridge), 1966-1967
Box 3
Beinert, Helmut, 1962
Box 3
C.H. Best, 1949-1950
Box 3
Biochemistry, Dept. of, 1947-1965
Box 3
Bridgers, William, 1965
Box 3
State University of New York at Buffalo lecture, 1965
Box 3
Clinical Chemistry Laboratory, 1941-1962
Box 3
Research in Dept. of Biochemistry, 1958-1962
Box 3
Bell Building Addition 4, 1958-1962
Box 3
Biophysics Committee, undated
Box 3
Brandeis University, undated
Box 3
A.H. Bryan to William Perlzweig, undated
Box 3
Carter, Herbert E., undated
Box 3
Commonwealth Fund and Research Training Program for Clinical Investigators, undated
Box 3
Congress (John Fogarty) and United States Senate (Lister Hill), undated
Box 3
Coolidge, Thomas B. to William A. Perlzweig, undated
Box 3
Biophysics Committee, 1950-1952
Box 4
Brandeis University, 1961-1963
Box 4
A.H. Bryan to William Perlzweig, 1946-1947
Box 4
Carter, Herbert E., 1939-1963
Box 4
Commonwealth Fund and Research Training Program for Clinical Investigators, 1956-1961
Box 4
Congress (John Fogarty) and United States Senate (Lister Hill), 1959-1963
Box 4
Coolidge, Thomas B. to William A. Perlzweig, 1935-1943
Box 4
Darby, William J., 1948-1949
Box 4
Davison, Wilburt Cornell, 1933-1963
Box 4
Deiss, William, 1954-1958
Box 4
Center for the Study of Aging, 1962-1963
Box 4
Training Program for Medical Investigators, correspondence with external pharmaceutical companies, 1957-1959
Box 4
NASA, 1962
Box 4
Biochemistry, Dept. of, Neurology committee materials, undated
Box 4
National Institutes of Health, research training grants, 1947-1961
Box 4
North Carolina College, 1960
Box 4
Nutrition Foundation, cira 1960-1966
Box 4
Office of Naval Research, 1949-1951
Box 4
Oregon State Talk, 1966
Box 4
Osborne And Mendel Award, 1959-1961
Box 4
Paul-Lewis Lab, 1962
Box 4
Pennsylvania Undergraduate Medical Association, 1966
Box 4
Pennsylvania Medical Society, 1965
Box 4
Rockefeller Foundation, 1956
Box 4
Rutgers Symposium, 1966
Box 4
Rutter, William J., 1957
Box 4
Saturday Review, 1963
Box 4
Scientists, Engineers, and Physicians for Johnson and Humphrey (political activism), 1964-1965
Box 4
Senez, Jacques, 1963
Box 4
Shell Fellowship, 1952-1954
Box 4
Shemin, David, 1953-1959
Box 4
Sigma Xi, 1964-1966
Box 4

2. Biographical Materials and Memoirs, 1961-1982

Scope and Contents note: Contains correspondence between Eric Handler and Robert Hill regarding the Handler estate and rights to works; clippings; special notices; programs; speeches; tributes; and remarks made about Dr. Handler following his death. The photograph of Philip Handler is oversized and undated.

Scrapbook materials, folder 1, 1961-1969
Box 5
Scrapbook materials, folder 2, 1961-1969
Box 5
Scrapbook materials, folder 3, 1961-1969
Box 5
Scrapbook materials, folder 4, 1961-1969
Box 5
Scrapbook materials, folder 5, 1961-1969
Box 5
Scrapbook materials, folder 6, 1961-1969
Box 5
Scrapbook materials, folder 7, 1961-1969
Box 5
Scrapbook materials, folder 8, 1961-1969
Box 5
Scrapbook materials, folder 9, 1961-1969
Box 5
Scrapbook materials, folder 10, 1961-1969
Box 5
Scrapbook materials, folder 11, 1961-1969
Box 5
Scrapbook materials, folder 12, 1961-1969
Box 5
Scrapbook materials, folder 13, 1961-1969
Box 5
Scrapbook materials, folder 14, 1961-1969
Box 5
Scrapbook materials, folder 15, 1961-1969
Box 5
Speeches and recognition, 1962-1981
Box 5
Biographical materials and remembrances, 1982
Box 5
Memorial service, 1982
Box 5
Philip Handler professorship, 1982
Box 5
Tribute, North Carolina School of Science and Math, 1982
Box 5
Other tributes, 1982
Box 5
Philip Handler memorial fund, 1982
Box 5
Photograph, undated
Box OS1

3. Reprints, 1939-1969

Staff Applications ( Old ), undated
Box 6
FASEB Advisory Comm., 1964-1965
Box 6
FASEB Advisory Comm., 1966
Box 6
Exams ( Old ), undated
Box 6
Exams ( Old ), undated
Box 6
Exams ( Old ), undated
Box 6
Exams, September 1967
Box 6
Studies Of Aldehyde Oxidase, by Electron Paramagnetic Resonance Spectroscopy I. Spectra At Equilibrium States, by K.V. Rajagopalen and Philip Handler; From The Journal of Biological Chemistry, vol. 243, No. 14, July 25, pp. 3784 - 3796, 1968, July 25, 1968
Box 6
Studies of Aldehyde Oxidase, by Electron Paramagnetic Resonance Spectroscopy II. Kinetic Studies, by Rapid Freezing by K.V. Rajagopalan and Philip Handler; From The Journal of Biological Chemistry, Vol. 243, No. 14, July 25, pp. 3798 - 3806, 1968, July 25, 1968
Box 6
The Role of Molybdenum In Xanthine Oxidase and Related Enzymes; Reactivity with Cyanide, Arsenite and Methanol, by MLP. Coughlan, K.V. Rajagopalan, and Philip Handler; From The Journal of Biological Chemistry, Vol. 244, No. 10, May 25, pp. 2658 - 2663, 1969, May 25, 1969
Box 6
Studies on Dihydroorotate Dehydrogenase, by Electron Paramagnetic Resonance Spectroscopy III. Kinetic Studies, by Rapid Freezing, by Victor Aleman and Philip Handler; From The Journal of Biological Chemistry, Vol. 243, No. 10, May 25, pp. 2569 - 2578, 1968, May 25, 1968
Box 6
Science and the Federal Government, by Philip Handler; Arch Dem. vol. 99, March, 1969, March, 1969
Box 6
The Young Scientist - Hour of Decision, Address, by Philip Handler; Presented at the Awards Banquet of the Science Talent Search for Westinghouse Science Scholarships and Awards, Sheraton Park Hotel, Washington, E.C., March 3, 1969, March 3, 1969
Box 6
Purification and Properties of Chicken Liver Xanthine Dehydrogenase, by K.V. Rajagopalan and Philip Handler, From The Journal of Biological Chemistry, vol. 242, No. 18, Sept. 25, pp. 4097 - 4107, 1967, September 25, 1967
Box 6
Federal Science Policy, by Philip Handler; From Science, March 3, 1967, vol. 155, No. 3766, pp. 1063 - 1066, March 3, 1967
Box 6
Academic Science And The Federal Government, by Philip Handler; From Science, Sept. 8, 1967, Vol. 157, No. 3793, pp. 1140 - 1146, September 8, 1967
Box 6
Phosphoglucomutase - Evolution of an Enzyme, by Philip Handler, T. Hashimoto, J.G. Joshi, H. Dougherty, K. Hanabusa, and C. del Rio; From Israel Journal of Medical Sciences, Vol. 1, No. 6, pp. 1173 - 1186, Nov. 1965, November 1965
Box 6
Purification and Properties of Xanthine Dehydrogemase from Micrococcus Lactilyticus, by Susan T. Smith, K.V. Hajagopalan, and Philip Handler; From The Journal of Biological Chemistry, vol. 242, No. 18, Sept. 25, pp. 4108 - 4117, 1967, September 25, 1967
Box 6
Preparation of Bovine Xanthine Oxidase and the Subunit Structures of Some Iron Flavoproteins, by Charles A. Nelson and Philip Handler; From The Journal of Biological Chemistry, Vol. 243, No. 20, Oct. 25, pp. 5368 - 5373, 1968, October 25, 1968
Box 6
Dihydroorotate Dehydrogenase I. General Properties, by Victor Aleman and Philip Handler; From The Journal of Biological Chemistry, Vol. 242, No. 18, Sept. 25, pp. 4087 - 4096, 1967, September 25, 1967
Box 6
Science And Public Policy - Second Annual Cushing Oration, by Philip Handler; From Journal of Neurosurgery, 1966, vol. XXV, No. 3, pp. 247 - 256, 1966
Box 6
Comparative Aspects of the Structure and Function of Phosphoglucomutase, by J.G. Joshi, T. Hashimoto, K. Hanabusa, H.W. Dougherty, and P. Handler; From Evolving Genes and Proteins, 1965, Academic Press, Inc., New York, NY, 1965
Box 6
Kinetics of Beef Heart Glutamic - Alanine Transaminase, by Bernard Bulos and Philip Handler; From The Journal of Biological Chemistry, vol. 240, No. 8, Aug., 1965, August, 1965
Box 6
National Planning For Medical Research, by Philip Handler; From Science, June 25, 1965, vol. 148, No. 3678, pp. 1699 - 1692, June 25, 1965
Box 6
Soluble Metalloflavoproteins, by V. Aleman, S.T. Smith, K.V. Rajagopalan, and P. Handler; From Non-Heme Iron Proteins: Hole In Energy Conversion, The Antioch Press, Yellow Springs, Ohio, 1965, 1965
Box 6
On The Mechanism of Action of Metalloflavoproteins, by victor .Aleman<Aleman, K.V1 Rajagopalan, and Philip Handler with Helmut Beinert and Graham Palmer; From Oxidases and Related Redox Systems, vols. 1 & 2, Published, by John Wiley & Sons, Inc., 1965, 1965
Box 6
Phosphoglucomutase - Evolution of an Enzyme, by Philip Handler, T. Hashimoto, J.G. Joshi, H. Dougherty, K. Hanalousa, and C. del Rio; From Israel Journal of Medical Sciences, Vol. 1, No. 6, pp. 1173 - 1186, Nov., 1965, November, 1965
Box 6
Problems In Energy Metabolism, by Philip Handler; From Science, Nov. 4, 1966, Vol. 154, No. 3749, p. 640, November 4, 1966
Box 6
On The Mechanism of Action of Some Soluble Metalloflavoproteins, by V. Alevan, S.T. Smith, K.V. Rajagopalan, and P. Handler; from Flavins and Flavogroteins, Elsevier Publishing Co., Ameterdam, 1966, 1966
Box 6
Science and Public Policy, Second Annual Cushing Oration, by Philip Handler; Reprinted from Journal of Neurosurgery, 1966, vol. XXV, No 3, pp. 247 - 256, 1966
Box 6
Phosophoglucomutase II. Preparation and Properties of Phosphoglucomutases From Micrococcus Lysodeikticus and Bacillus Cereus, by K. Hanabusa, H.W. Dougherty, C. del Rio, Takashe Hashimoto, and Philip Handler; From The Journal of Biological Chemistry, Vol. 241, No. 17, Sept. 10, pp. 3930 - 3939, 1966, September 10, 1966
Box 6
Phosphoglucomutase III. Purification and Properties of Phosphoglucomutases from Flounder and Shark Muscle, by Takashi Hashimoto and Philip Handler; From The Journal of Biological Chemistry, vol. 241, No. 17, Sept. 10, pp. 3940 - 3948, 1966, September 10, 1966
Box 6
Phosphoglucomutase IV. Inactivation, by Beryllium Ions, by Takashi Hashimoto, Jayant G. Joshi, C. del Rio, and Philip Handler; From The Journal of Biological Chemistry, Vol. 242, No. 8, April 25, pp. 1671 - 1679, 1967, April 25, 1967
Box 6
Phosphoglucomutase V. Multiple Forms of Phosphoglucomutase, by J.G. Joshi, J. Hooper, T. Kuwaki, T. Sakurada, J.R. Swanson, and P. Handler; From Proceedings of the National Academy of Sciences, Vol. 57, No. 5, pp. 1482 - 1489, May, 1967, May, 1967
Box 6
Some Major Issues Concerning The Support of Fundamental Research and Graduate Education in Science, by Philip Handler; Adopted from a Statement Presented at a Symposium at the Annual Meeting of the National Research Council, Washington, March 11, 1967, March 11, 1967
Box 6
Structure and Function of Metalloflavoproteins, by P. Handler and K. V. Rajagopalan; Given at the Seventh International Congress of Biochemistry, Tokyo, Aug. 19 - 25, 1967, August 19-25, 1967
Box 6
Architecture Appropriate to the Conduct of Science, by Philip Handler; From Bulletin of the American Meteorological Society, Vol. 48, No. 7, July, 1967, p. 447, July, 1967
Box 6
A Time of Transition Current Issues in Medical School-University Relations, by Philip Handler; From The Journal of Medical Education, vol. 42, No. 7, July, 1967, July, 1967
Box 6
Dihydroorotate Dehydrogenase I. General Properties, by Victor Aleman and Philip Handler; From The Journal of Biological Chemistry, vol. 242, No. 18, Sept. 25, pp. 4087 - 4096, 1967, September 25, 1967
Box 6
Hepatic Aldehydy Oxidase II. Differential Inhibition of Electron Transfer to Various Electron Acceptors, by K.V. Hajagopalan and Philip Handler; Fron The Journal of Biological Chemistry, vol. 239, No. 6, June, 1964, June, 1964
Box 6
Hepatic Aldehyde Oxidase III. The Substrate-Binding Site, by K.V. Rajagopalan and Philip Handler; From The Journal of Biological Chemistry, Vol. 239, No. 6, June, 1964, June, 1964
Box 6
Phosoglucomutase I. Purification and Properties of Phosphoglucomutase From Escherichia Coli, by Jayant G. Joshi and Philip Handler; From The Journal of Biological Chemistry, vol. 239, No. 9, Sept., 1964, September, 1964
Box 6
The Metabolism of N-Substituted Amino Acids, by Philip Handler; An Abstract of a Thesis - Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy in Chemistry in the Graduate School of the University of Illinois, Urbana, Illinois, 1939, 1939
Box 6
Azlactones I. Preparation of Benzoyl - a - Aminocrotonic Acid Azlactone and the Conversion of Allo-Threonine to Threonine, by Herbert E. Carter, Philip Handler, and Donald B. Melville; From The Journal of Biological Chemistry, vol. 129, No. 1, July, 1939, July, 1939
Box 6
Metabolism of NaAlkyl Derivatives of Amino Acids, by Herbert E. Carter and Philip Handler; From Proceedings of the Society for Experimental biology and Medicine, 1939, 41, 347 - 348, 1939
Box 6
The Reaction of Formaldehyde with Amino Acids: X-Ray Diffraction Patterns, by Allan K. Smith and Philip Handler and J.N. Mequdich; From The Journal of Physical Chemistry, vol. 44, No. 7, Oct., 1940, October, 1940
Box 6
Catalytic .Action of 8-Hydroxyquinoline on the Oxidation of B-PHaemylenediamine, by Frederick Bernheim and Philip Handler; From Journal of the American Chemical Society, 62, 984 (1940), 1940
Box 6
The Effect of Pyrazine Acids and Quinolinic Acid on the V-Factor Content of Human Blood and Upon Canine Blacktongue, by W.J. Dann, H.I. Kohn, and P. Handler; From J. of Nutrition, V. 20, No. 5, Nov. 11, 1940, November 11, 1940
Box 6
The Nicotinic Acid and Coenzyme Content of the Tissues of Normal And Blacktongue Dogs, by W.J. Dann and Philip Handler; From J. Nutrition, V. 22, No. 4, Oct. 10, 1941, October 10, 1941
Box 6
The Present Status of Nicotinic Acid, by Philip Handler, Oct. 11, 1947, October 11, 1947
Box 7
Protein As A metabolic Fuel, by P. Handler; Reprinted from Brookhaven Symposia In Biology No. 5. (BNL 206 [C-15]), September, 1952
Box 7
The Young Scientist - Hour of Decision - Address, by Philip Handler, Ph.D., President-elect, National Academy of Sciences, March 3, 1969, March 3, 1969
Box 7
Federation Proceedings - Nutritional Diseases, Sept., 1958, Vol. 17, Supp. No. 2, No. 3, Part II, 1958
Box 7
Science and Public Policy Second Annual Cushing Oration, by Philip Handler; Reprinted from Journal of Neurosurgery, 1966, Vol. XXV, No. 3, pp. 247 - 256, 1966
Box 7
Discussion of Reports on Renoprival Hypertension; Reprinted from Circulation, Vol. XVII, No. 4, April, 1958, April, 1958
Box 7
Conference On Mechanism of Protective Action of Kidney and Relation of Renoprival to Chronic Renal Hypertension, Led, by E. Braun-Menendez, M.D.; Reprinted from Circulation, Vol. XVII, No. 4, April, 1958, April, 1958
Box 7
Biosynthesis of Diphosphoryridine Nucleotide by Jack Preiss (Intr., by C.E. Anderson); Reprinted from Federation Proceedings, vol. 17, No. 1, March, 1958, March, 1958
Box 7
Partial Purification and Properties of Renal Glutaminase, by Jack D. Klingman and Philip Handler; Reprinted from The Journal of Biological Chemistry, Vol. 232, No. 1, May, 1958, May, 1958
Box 7
Metabolism of Nicotonic Acid and the Pyridine Nucleotides, by Philip Handler; Reprint of a paper to be read at the IVth International Congress of Biochemistry, Vienna, 1-6 Sept. 1958, September 1-6, 1958
Box 7
Kinetics of Ammonia Metabolism in vivo, by George D. Duda and Philip Handler; Reprinted from The Journal of Biological Chemistry, Vol. 232, No. 1, May, 1958, May, 1958
Box 7
Intermediates in the Synthesis of Diphosphopyridine Nucleotide from Nicotinic Acid, by Jack Preiss and Philip Handler; Reprinted from the American Chemical Society, 79, 4246 (1957), 1957
Box 7
Colorimetric Assay for Reaction of Sulfhydryl Groups with Organic Mercurials, by Irwin Fridovich and Philip Handler; Reprinted from Analytical Chemistry, Vol. 29, No. 8, pp. 1219 - 1220, Aug., 1957, August, 1957
Box 7
Amino Acid and Protein Metabolism, by H. Kamin and P. Handler; Reprinted from Annual Review of Biochemistry, Vol. 26, 1957, 1957
Box 7
Instrumental Artifacts in the Determination of Difference Spectra, by Irwin Fridovich, Walter Farkas, George W. Schwert, Jr., and Philip Handler; Reprinted from Science, June 7, 1957, vol. 125, No. 3258, pp. 1141 - 1142, June 7, 1957
Box 7
Influence of Sulfhydryl Compounds on the Equilibrium of the Alcohol Dehydrogenase Reaction, by Robert M. MacLeod, Irwin Fridovich, and Philip Handler; Reprinted from Archives of biochemistry and Biophysics, Vol. 72, No. 1, Nov., 1957, November, 1957
Box 7
Xanthine Oxidase I. The Oxidation of Sulfite, by Irwin Fridovich and Philip Handler; Reprinted from The Journal of Biological Chemistry, Vol. 228, No. 1, Sept., 1957, September, 1957
Box 7
A Colorimetric Micromethod for Determination of Ammonia: The Ammonia Content of Rat Tissues and Human Plasma, by Rose H. Brown, George D. Duda, Seymour Korkes and Philip Handler; Reprinted from Archives of Biochemistry and Biophysics, Vol. 66, No. 2, Feb., 1957, February, 1957
Box 7
Cuff for Use with Endpoint Devices for Estimation of Arterial Blood Pressure of the Rat by Theodore Rosett and Philip Handler; Reprinted from Proceedings of the Society for Experimental Biology and Medicine, 1957, V. 96, 391 - 392, 1957
Box 7
Enzymatic Synthesis of Nicotinamide Mononucleotide, by Jack Preiss and Philip Handler; Reprinted from The Journal of Biological Chemistry, vol. 225, No. 2, April, 1957, April, 1957
Box 7
Synthesis of Diphosphopyridine Nucleotide from Nicotinic Acid, by Human Erythocytes in vitro, by J. Preiss and Philip Handler; Reprinted from the Journal of the American Chemical Society, 79, 1514 (1957), 1957
Box 7
Stimulation, by Dinitrophenol of Formation of Melanin-Like Substance from Tyrosine, by Rat Liver Homogenates, by Henry Kamin, Mildred A. Koon, and Philip Handler; Reprinted from The Journal of Biological Chemistry, vol. 224, No. 2, April, 1957, April, 1957
Box 7
Partial Purification of Renal Glutaminase, by Jack D. Klingman and Philip Handler; Reprinted from Federation Proceedings, Vol. 16, No. 1, March, 1957, March, 1957
Box 7
Les Dernieres Etapes De L0xydation De La Cysteine: L0xydation Du Sulfite, by P. Handler et I. Fridovich, from Collogue Sur La Biochimie Du Soufre, 14-18 Mai 1956, May 1956
Box 7
Sulfite Oxidation, by Xanthine Oxidase, by Irwin Fridovich and Philip Handler; Reprinted from Inorganic Nitrogen Metabolism, Edited, by William D. McElroy and Bentley Glass; The Johns Hopkins Press, Baltimore, 1956, 1956
Box 7
Inhibition, by Dinitrophenol of the Phosphate- Dependent Catalysis of Sulfite Oxidation, by Metals, by Irwin Fridovich and Philip Handler; Reprinted from Federation Proceedings, vol. 15, No. 1, March, 1956, March, 1956
Box 7
Nutrition and Cardiovascular Disease, by Philip Handler, Ph.D., Reprinted from Geriatrics, vol. 11, pp. 229, May, 1956, May, 1956
Box 7
Hypoxanthine, Cofactor for Cysteine Oxidation, by Liver Preparations, by Irwin Fridovich and Philip Handler; Reprinted from Biochin. et Biogh. Acta Vol. 21 (1956), 1956
Box 7
Hypoxanthine As 1A Cofactor for the Enzymatic Oxidation of Sulfite, by Irwin Fridovich and Philip Handler; Reprinted from The Journal of Biological Chemistry, Vol. 221, No. 1, July, 1956, July, 1956
Box 7
Pressor Factor in Normal Human Urine, by Philip Handler; Reprinted from The American Journal of Physiology, vol. 184, No. 2, February, 1956, February, 1956
Box 7
The Initial Step in Enzymatic Sulfite Oxidation, by Irwin Fridovich and Philip Handler; Reprinted from The Journal of Biological Chemistry, vol. 223, No. 1, Nov., 1956, November, 1956
Box 7
Fatty Liver Induced, by Orotic Acid Feeding, by Susan B. Standerfer and Philip Handler; Reprinted from Proceedings of the Society for Experimental Biology and Medicine, 1955, V. 90, 270 - 271, 1955
Box 7
Hypoxanthine, Coenzyme of Sulfite Oxidase, by Irwin Fridovich and Philip Handler; Reprinted from Federation Proceedings, vol. 14, No. 1, March, 1955, March, 1955
Box 7
Sulfite Metabolism In E. Coli, by F1A. Cobey and Philip Handler; Elsevier Publishing Co., Feburary, 1956
Box 7
Non-Enzymatic Formation of Melanin-like Substance from dl-Tyrosine-2-C14 In The Presence of Polyphenols and Quinones, by Henry Kamin, Mildred A. Koon, and Philip Handler; Reprinted from Federation Proceedings, vol. 14, No. 1, March, 1955, March, 1955
Box 7
Stimulation, by 2,4-Dinitrophenol, 3,4- Dihydroxyphenylalanine, and Homogentisic Acid, of uptake of Radioactivity From DL-Tyrosine-2-C14, by Rat Liver Proteins in vitro, by Henry Kamin, Mildred Koons, and Philip Handler; Reprinted from Federation Proceedings, vol. 13, No. 1, March, 1954, March, 1954
Box 7
Mechanism of Esterase Action, by Philip Handler and Beverly B. Stewart; Reprinted from Federation Proceedings, Vol. 13, No. 1, March, 1954, March, 1954
Box 7
Further Studies of Sulfite Oxidase, by Irwin Fridovich and Philip Handler; Reprinted from Federation Proceedings, vol. 13, No. 1, March, 1954, March, 1954
Box 7
Mechanism of Thiamine-Catalyzed Reactions, by Shunzi Mizuhara and Philip Handler; Reprinted from The Journal of The American Chemical Society, 76, 571 (1954), 1954
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Radiation and Aging, by Philip Handler; Reprinted from Aging, American Association for the Advancement of Science, Copyright 1960, 1960
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Adenylate Kinase Activity in vivo, by Flora-Pearl Cobey and Philip Handler; Reprinted from Federation Proceedings, Vol. 12, No. 1, March, 1953, March, 1953
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Renal Phosphate and Carbohydrate Metabolism Studied with the Aid of Radiophosphorus, by Arthur F. Dratz and Philip Handler; Reprinted from The Journal of Biological Chemistry, vol. 197, No. 1, July, 1952, July, 1952
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Apparent Adenylate Kinase Activity in Vivo., by Florapearl A. Cobey and Philip Handler; Reprinted from The Journal of Biological Chemistry, vol. 204, NO. 1, Sept., 1953, September, 1953
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The Enzymatic; Oxidation of Sulfite, by Murray Heimberg, Irwin Fridovich, and Philip Handler; Reprinted from The Journal of Biological Chemistry, vol. 204, No. 2, Oct., 1953, October, 1953
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Influence of Previous Dietary Protein and of ACTH on Block Blucose Concentration of Fasting Rats, by Philip Handler and Ruth 8. Georgiade; Reprinted from The American Journal of Physiology, vol. 164, No. 1, Jan., 1951, January, 1951
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Metabolism of Methylnicotinamide, by the Liver of Rats, Rabbits and Guinea Pigs in vitro, by Sylvia F. Hunter and Philip Handler; Reprinted from Archives of Biochemistry and Biophysics, vol. 35, No. 2, Feb., 1952, pp. 377 - 383, February, 1952
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Enzymatic Oxidation of Bisulfite, by Rat Liver, by Murray Heimberg and Philip Handler; Reprinted from Federation Proceedings, vol. 11, No. 1, March, 1952, March, 1952
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Effect of Presence of Other Amino Acids Upon Intestinal Absorption of Single Amino Acids in the Rat, by Henry Kamin and Philip Handler; Reprinted from The American Journal of Physiology, vol. 169, No. 2, May, 1952 Philip Handler and David V. Cohn, May, 1952
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Effect of Parathyroid Extract on Renal Function, by Philip Handler and David V. Cohn; Reprinted from The American Journal of Physiology, Vol. 169, No. 1, April, 1952, April, 1952
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The Biochemical Basis for Reval Hypertension, by P. Handler and F. Bernheim; Reprinted from Journal of Gerontology, Vol. 6, Supplement No. 3, 1951, p. 98, 1951
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Effects of Caloric Restriction, Salt Restriction, and Role of Pituitary and Adrenal Glands in Experimental Renal Hypertension, by Philip Handler and Frederick Bernheim; Reprinted from The American Journal of Physiology, Vol. 166, No. 3, Sept., 1951, September, 1951
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Effect of Parathyroid Extract on Renal Excretion of Phosphate, by Philip Handler, David V. Cohn, and W.J.A. DeMaria; Reprinted from The American Journal of Physiology, Vol. 165, No. 2, May, 1951, May, 1951
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Effect of Renal Decapsulation on Hypertension Induced, by Single Episode of Acute Choline Deficiency, by Philip Handler and Frederick Bernheim; Reprinted from Proceedings of the Society for Experimental Biology and Medicine, 1951, V. 76, 338-341, 1951
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The Metabolism of Parenterally Administered Amino Acids II. Urea Synthesis, by Henry Kamin and Philip Handler; Reprinted from The Journal of Biological Chemistry, Vol. 188, No. 1, Jan., 1951, January, 1951
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The Metabolism of Parenterally Administered Amino Acids III. Amonia Formation, by Henry Kamin and Philip Handler; Reprinted from The Journal of Biological Chemistry, Vol. 193, No. 2, Dec., 1951, December, 1951
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Maximum Rate of Urea Production from various Amino Acids in the Dog, by Henry Kamin and Philip Handler; Reprinted from Federation Proceedings, Vol. 9, No. 1, March, 1950, March, 1950
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Physiological Basis for Effects of Low Protein Diets on Blood Pressure of Subtotally Nephrectomized Rats, by Philip Handler and Frederick Bernheim; with Technical Assistance from Eunice Matthews and Ludie Avery; Reprinted from The American Journal of Physiology, Vol. 162, No. 2, August, 1950, August, 1950
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Synthesis of Unusual Quantities of Pyridine Nucleotides, by Human Erythrocytes, In Vitro, by Irwin G. Leder, WHA. Perlzweig and Philip Handler; Reprinted from Federation Proceedings, Vol. 9, No. 1, March, 1950, March, 1950
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Diminished ACTH Production in Rats on Low Protein Diets; Explanation of Relationship Between Dietary Protein and Renal Hypertension, by Philip Handler and Frederick Bernheim; Reprinted from Federation Proceedings, vol. 9, No. 1, March, 1950, March, 1950
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Effect of Choline Deficiency on ACTH Production and on Hypertension of Subtotally Nephrectomized Rats, by Philip Handler and Frederick Bernheim; with the Technical Assistance of Eunice Matthews and Ludie Avery; Reprinted from The American Journal of Physiology, Vol. 162, No. 2, Aug., 1950, August, 1950
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Influence of Dietary Factors on Hypertension Induced, by Choline Deficiency, by Philip Handler and Frederick Bernheim; Reprinted from The American Journal of Physiology, Vol. 162, No. 1, July, 1950, July, 1950
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Synthesis of Nicotinamide Mononucleotide, by Human Erythrocyte Hemolystates, by Irwin G. Leder and Philip Handler; Reprinted from Phosphorus Metabolism, Vol. 1, Edited, by William D. McElroy and Bentley Glass, The Johns Hopkins Press, Baltimore, 1951, 1951
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Influence of Age on Hepatic Response to Choline and Cystine Deficiency in the Rat, by Philip Handler and Richard H. Follis, Jr.; Reprinted from Proceedings of the Society for Experimental Biology and Medicine; 1950, V. 75, 567 - 570, 1950
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The Metabolism of Parenterally Administered Amino Acids I. Glycine, by Philip Handler, Henry Kamin, and Jerome S. Harris; Reprinted from The Journal of Biological Chemistry, vol. 179, No. 1, May, 1949, May, 1949
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Mode of Action of Parathormone, by Philip Handler, W.J.A. DeMaria, and D.V. Cohn; Reprinted from Federation Proceedings, Vol. 8, No. 1, March, 1949, March, 1949
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Whipples Intestinal Lipodystrophy, by James P. Hendrix, Bernard Black-Shaffer, Robert W. Withers, and Philip Handler; Reprinted from The Archives of Internal Medicine, Jan., 1950, vol. 85, pp. 91 - 131, January, 1950
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Importance of Dietary Protein, Calories and Salt in Experimental Renal Hypertension, by Philip Handler and Frederick Bernheim; Reprinted from The American Journal of Physiology, Vol. 160, No. 1, Jan., 1950, January, 1950
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Ammonia Production, by Kidney Slices of Normal, Acidotic and Alkalotic Rats, by Philip Handler, F. Bernheim and M.L.C. Bernheim; Reprinted from Archives of Biochemistry, Vol. 21, No. 1, March, 1949, pp. 132 - 134, March, 1949
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Choline Deficiency in the Hamster, by Philip Handler and Frederick Bernheim; Reprinted from Proceedings of the Society for Experimental Biology and Medicine, 1949, V. 72, 569 - 571, 1949
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Response of Guinea Pigs to Diets Deficient in Choline, by Philip Handler; Reprinted from Proceedings of the Society for Experimental Biology and Medicine, 1949, 70, 70 - 73, 1949
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William John Dann 1904 - 1948, by Philip Handler; Reprinted from Science, July 8, 1949, Vol. 110, No. 2845, page 51, July 8, 1949
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The Use of Positron-emitting Radioisotopes for the Localization of Brain Tumors, by Frank R. Wrenn, Jr., Myron L. Good, and Philip Handler; Reprinted from Science, May 4, 1951, vol. 113, No. 2940, pp. 525 - 527, May 4, 1951
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Basis for Experimental Renal Hypertension, by Philip Handler and Frederick Bernheim; Reprinted from Federation Proceedings, March, 1951, vol. 10, No. 1, Part 1, March, 1951
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Synthesis of Nicotinamide Mononucleotide, by Human Erythrocytes in vitro, by Irwin G. Leder and Philip Handler; Reprinted from The Journal of Biological Chemistry, Vol. 189, No. 2, April, 1951, April, 1951
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Use of Radiophosphorus in Studies of Glomerular Permeability of Plasma Inorganic Phosphate, by Philip Handler and David V. Cohn; Reprinted from The American Journal of Physiology, Vol. 164, No. 3, March, 1951, March, 1951
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Effect of Infusion of Single Amino Acids Upon Excretion of Other Amino Acids, by Henry Kamin and Philip Handler; Reprinted from The American Journal of Physiology, vol. 164, No. 3, March, 1951, March, 1951
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A Fluorimetric Assay for N-Methyl-6-Pyridone-3- Carboxylamide, by Fred Rosen, W.A. Perlzweig and Philip Handler; Reprinted from Federation Proceedings, Vol. 7, No. 1, March, 1948, March, 1948
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The Influence of Thyroid Activity on the Liver and Plazma Lipides of Choline - And - Cystine-Deficient Rats, by Philip Handler; Reprinted from The Journal of Biological Chemistry, vol. 173, No. 1, March, 1948, March, 1948
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Xanthine Oxidase I. The Oxidation of Sulfite, by Irwin Fridovich and Philip Handler; Reprinted from The Journal of Biological Chemistry, vol. 228, No. 1, Sept., 1957, September, 1957
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Kinetics of Ammonia Metabolism in vivo, by George D. Duda and Philip Handler; Reprinted from The Journal of Biological Chemistry, vol. 232, No. 1, May, 1958, May, 1958
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The Role of Thyroid Activity in the Pathogenesis of Hepatic Lesions Due to Choline and Cystine Deficiency, by Philip Handler and Richard H. Follis, Jr.; From Journal of Nutrition, V. 35, No. 6, June, 1948, pp. 669 - 688, June, 1948
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The Absorption Spectra of Iron-Flavoproteins, by K.V. Rajagopalan and Philip Handler; From The Journal of Biological Chemistry, Vol. 239, No. 5, May, 1964, May, 1964
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Biochemistry Symposium-Biochemical Evolution - Introductory Remarks, by Philip Handler; Reprinted from Federation Proceedings, Vol. 23, No. 6, Nov/Dec., 1964, November-December, 1964
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Biochemistry Symposium - Science and Public Policy - Preliminary Remarks, by Philip Handler; Reprinted from Federation Proceedings, Vol. 23, No. 6, Nov- Dec., 1964, November-December, 1964
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Structure and Function of Iron-Flavoproteins, by P. Handler, K.V. Rajagopalan, and V. Aleman; Reprinted from Federation Proceedings, Vol. 23, No. 1, Jan.- Feb., 1964, January-February, 1964
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Evolution of the Coenzymes, by Philip Handler; Reprinted from Proceedings of The Fifth International Congress of Biochemistry, Vol. II, Pergamon Press, 1963, 1963
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The Effect of Research Emphasis on Research Itself; B. Two Schools of Thought on the Results of Expanding Research Support, An Optimistic View, by Philip Handler; Reprinted from Research and Medical Education, Vol. 37, No. 12, Dec., 1962, December, 1962
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The Presence of Two Species of DNA In Some Halobacteria, by J.G. Joshi, W.R. Guild, and P. Handler; From J. Mol. Biol. (1963) 6, 34 - 38, 1963
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Xanthine Oxidase V. Differential Inhibition of the Reduction of Various Election Acceptors, by Irwin Fridovich and Philip Handler; From The Journal of Biological Chemistry, Vol. 237, No. 3, March, 1962, March, 1962
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Xanthine Oxidase VI. Influence of pH on Substrate Specificity, by Louance Greenlee and Philip Handler; From The Journal of Biological Chemistry, Vol. 239, No. 4, April, 1964, April, 1964
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Xanthine Oxidase VII. Inhibition, by Amino Group Reagents, by Lorance Greenlee and Philip Handler; From The Journal of Biological Chemistry, vol. 239, No. 4, April, 1964, April, 1964
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Metabolism of Trigonelline, by Jayant G. Joshi and Philip Handler; From The Journal of biological Chemistry, vol. 237, No. 10, Oct., 1962, October, 1962
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The Absorption Spectra of Iron-Flavoproteins, by K.V; Rajagopalan and Philip Handler; From Lag Journal of Biological Chemistry, vol. 239, No. 5, May, 1964, May, 1964
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Preparation of Several Forms of Xanthine Oxidase, by Enzymic Proteolysis, by Francis 6. Carey, Irwin Fridovich and Philip Handler; Reprinted from Biochem. Biophys., te (1961) 440 - 442, 1961
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Hepatic Aldehyde Oxidase I. Purification and Properties, by K. V. Rajagopalan, Irwin Fridovich and Philip Handler; From The Journal of Biological Chemistry, Vol. 237, No. 3, March, 1962, March, 1962
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Purification and Properties of Nicotinamidase from Torula Cremoris, by Jayant G. Joshi and Philip Handler; From The Journal of Biological Chemistry, Vol. 237, No. 3, March, 1962, March, 1962
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Oxidation of Phenazine Methosulfate, by Hepatic Aldehyde 0xidase, by K. V. Rajagopalan and Philip Handler; From Biochemical and Biophysical Research Communications, Vol. 8, No. 1, 1962, 1962
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Electron Paramagnetic Resonance Studies of Iron Reduction and Semiquinone Formation in Metalloflavoproteins, by K.V. Rajagopalan, victor Aleman and Philip Handler; From Biochemical and Biophysical Research Communications, vol. 8, No. 3, 1962, 1962
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Chemiluminescence Induced, by Operation of Iron- Flavoproteins, by Lorance Greenlee, Irwin Fridovich and Philip Handler; From Biochemistry, i, 779 (1962), 1962
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Enzyme Illustration, undated
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Illustration, undated
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Phosphoglucomutases, undated
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Correspondence Re: Publishing of Principles of Biochemistry, by Abraham white, Ph.D.; Philip Handler, Ph.D.; Emil L. Smith, Ph.D.; Dewitt Stetten, Jr., M.D., Ph.D.; 1953, 1954, 1953, 1954
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Handler - Unfinished Book Notes, undated
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More book Correspondence, undated
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Correspondence Re: Publishing of Principles of Biochemistry, 1956 - 1958, 1956-1958
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Book Correspondence, Section V, undated
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The Effect of Research Emphasis on Research Itself; B. Two Schools of thought on the Results of Expanding Research Support, An Optimistic View, by Philip Handler; Reprinted from Research and Medical Education, 1962, 1962
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Preparation of Several Forms of Xanthine Oxidase, by Enzymic Proteolysis, by F.G. Carey, I. Fridovich, and P. Handler; Reprinted from Biochimica et Bioghysica Acta; Elsevier Publishing Co., Amsterdam, October 1961
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Introduction, by Philip Handler; Reprinted from Federation Proceedings, vol. 20, No. 2, Pt. 2, July 8, 1961, July 8, 1961
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Biochemical Considerations of Relationships Between Effects of Time and of Radiation on Living Systems, by Philip Handler; Reprinted from Federation Proceedings, Vol. 20, No. 2, Pt. 2, July 8, 1961, July 8, 1961
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Inactivity of Nicotinuric Acid in Canine Blacktongue, by W. J. Dann and P. Handler (Introduced by S.A. Perlzweig), Reprinted from Proceedings of the Society for Experimental Biology and Medicine, 1941, 48, 355 - 366, 1941
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Oxidation of Some Substituted Alcohols, by Rat Liver, by Frederick Bernhiem and Philip Handler (Introduced, by WLA. Perlzweig); Reprinted from Proceedings of the Society for Experimental biology and Medicine, 1941, 46, 470 - 471, 1941
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The Inactivation of Pyridine Nucleotides, by Animal Tissues in vitro, by Philip Handler and J. Raymond Klein; Reprinted from The Journal of Biological Chemistry, Vol. 143, No. 1, March, 1942, March, 1942
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The Nicotinic Acid Content of Meat, by Dann, W.J. and P. Handler; Reprinted from J. Nutrition, V. 24, No. 2, Aug. 10, August 10 1942
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The Biochemical Defect in Nicotinic Acid Deficiency II. On the Nature of the Anemia, by Philip Handler and William P. Featherston; Reprinted from The Journal of Biological Chemistry, Vol. 151, No. 2, Dec., 1943, December, 1943
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Use of Highly Purified Rations in the Study of Nicotinic Acid Deficiency, by Philip Handler (Introduced, by W.A. Perlzweig); Reprinted from Proceedings of the Society for Experimental biology and Medicine, 1943, 52, 263 - 264, 1943
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The Effect of Choline Deficiency on the Fat Content of Regenerated Liver, by Philip Handler and Frederick Bernheim; Reprinted from The Journal of Biological Chemistry, vol. 148, No. 3, June, 1943, June, 1943
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The Effect of Simultaneous Mineral and Choline Deficiencies on Lover Fat, by Philip Handler; Reprinted from The Journal of Biological Chemistry, vol. 149, No. 1, July, 1943, July, 1943
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Animal Experiments with Tannic Acid, Suggested, by the Tannic Acid Treatment of Burns, by Roger D. Baker, MLD., and Philip Handler, Ph.D.; Reprinted from Annals of Surgery, Vol. 118, No. 3, Sept., 1943, September, 1943
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The Specificity of 1(-) - Methionine in Creatine Synthesis, by Philip Handler and Mary L.C. Bernheim, Reprinted from The Journal of Biological Chemistry, Vol. 150, No. 2, Oct., 1943, October, 1943
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The Effect of Excessive Nicotinamide Feeding on Rabbits and Guinea Pigs, by Philip Handler; Reprinted from The Journal of Biological Chemistry, vol. 154, No. 1, June, 1944, June, 1944
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The Toxicity of Orally Administered Tannic Acid, by Philip Handler and roger D. Baker; Reprinted from Science, May 12, 1944, Vol. 99, No. 2576, p. 393, May 12, 1944
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Alleviation, by Raw Liver of Anorexia Produced, by Sulfapyridine, by Philip Handler (Introduced, by WHA. Perlzweig); Reprinted from Proceedings of the Society for Experimental Biology and Medicine, 1944, 57, 99 - 101, 1944
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The Effects of various Inhibitors of Carbohydrate Metabolism, In vivo, by Philip Handler; Reprinted from The Journal of Biological Chemistry, vol. 161, No. 1, Nov., 1945, November, 1945
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Detoxication Mechanisms, by Philip Handler and William A. Perlzweig; Reprinted from Annual Review of Biochemistry, Vol. XIV, 1945, 1945
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Dietary Factors in the Regulation of Liver Lipid Concentration, by Philip Handler; Reprinted from The Journal of Biological chemistry, Vol. 162, No. 1, Jan., 1946, January 1946
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The Failure of Skeletal Calcification Produced, by High Lactose and, by Simple Caloric restriction, by Philip Handler (Introduced, by W.J. Dann); Reprinted from Federation Proceedings, vol. 5, No. 1, March, 1946, March, 1946
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The Significance of Fatty Infiltration in the Development of Hepatic Cirrhosis Due To Choline Deficiency, by Handler, Philip and I.N. Dubin; From J. Nutrition, v. 31, No. 2, February, February, 1946
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The Effects of Insulin in Fluoride - Poisoned Rats, by Philip Handler, Howard E. Herring, Jr., and John H. Hebb; Reprinted from The Journal of biological Chemistry, vol. 164, No. 2, August, 1946, August, 1946
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The Biochemical Defect Underlying the Nutritional Failure of Young Rats on Diets Containing Excessive Quantities of Lactose or Galactose, by Handler, Philip; J. Nutrition, V. 33, No. 2, February; pp. 221 - 234, February, 1947
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Influence of Thyroid Activity on Liver Lipids in Choline and Cystine Deficiency, by Philip Handler; Reprinted from Federation Proceedings, Vol. 6, No. 1, March, 1947, March, 1947
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The Significance of Parathyroid Activity in Physiological Regulation of Acid-Base Balance, by Philip Handler and John McCoy; Reprinted from Federation Proceedings, vol. 6, No. 1, March, 1947, March, 1947
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The Effects of Caloric Restriction on Skeletal Growth, by Handler, Philip, George J. Baylin and R.H. Follis, Jr; J. Nutrition, V. 34, No. 6, Dec., pp. 677 - 690, December 1947
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Metabolic Complexities of Pellagra by Philip Handler; Reprinted from The Journal of Laboratory and Clinical Medicine, vol. 32, No. 4, April, 1947, pp. 428 - 436, April, 1947
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Nitrogen Balance, by Philip Handler; Reprinted from The Journal of Laboratory and Clinical Medicine, Vol. 32, No. 4, April, 1947, pp. 437 - 443, April, 1947
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Indoleacetic Acid and Growth of Bacteria With Varying Requirements for Nicotinic Acid and Tryptophane, by Philip Handler and Henry Kamin; Reprinted from Proceedings of the Society for Experimental Biology and Medicine, 1947, 66, 251 - 254, 1947
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The Determination of Choline in Biological Material, by Philip Handler; Reprinted from Biological Symposia, Vol. XII, 1947, 1947
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Dietary Factors in Experimental Renal Hypertension I. Protein, by Philip Handler and F. Bernheim; reprinted from Federation Proceedings, vol. 7, No. 1, March, 1948, March, 1948
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The Metabolism of Parenterally Administered Amino Acids I. Glycine;, by Philip Handler, Henry Kamin and Jerome S. Harris; Reprinted from Federation Proceedings, Vol. 7, No. 1, March, 1948, March, 1948
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Metabolism of Trigonelline, by Jayant G. Joshi and Philip Handler; Reprinted from The Journal of Biological Chemistry, Vol. 237, No. 10, Oct., 1962, October, 1962
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Contributions of Biochemical Research to Progress in Medicine, by Philip Handler, Ph.D., Reprinted from The Journal of The American Medical Association, Sept. 23, 1961, Vol. 177, pp. 840 - 849, September 23, 1961
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Effects of Parathyroid Extract on Sulfate Metabolism of Cartilage an Bone Matrix of Rachitic Rats, by Daviel S. Bernstein and Philip Handler; Reprinted from Proceedings of the Society for Experimental Biology and Medicine, 1958, V. 99, 339 - 340, 1958
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Xanthine Oxidase II. Studies of the Active Site, by Irwin Fridovich and Philip Handler; Reprinted from The Journal of Biological Chemistry, Vol. 231, No. 2, April, 1958, April, 1958
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Xanthine Oxidase III. Sulfite Oxidation as an Ultra Sensitive Assay, by Irwin Fridovich and Philip Handler; Reprinted from The Journal of Biological Chemistry, Vol. 233, No. 6, Dec., 1958, December, 1958
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Xanthine Oxidase IV. Participation of Iron In Internal Electron Transport, by Irwin Fridovich and Philip Handler; Reprinted from The Journal of Biological Chemistry, Vol. 233, No. 6, Dec., 1958, December, 1958
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Sulfite Oxidation in Rat Liver, by Irwin Fridovich, Walter Farkas, and Philip Handler; From Bulletin di la Societe Chimie Biologigue, Extrait du Tome XL, No. 12, 1958, pp. 1795 - 1801, 1958
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Partial Purification and Properties of Renal Glutaminase, by Jack D. Klingman and Philip Handler; Reprinted from The Journal of Biological Chemistry, vol. 232, No. 1, May, 1958, May, 1958
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994. Mitochondrial Binding of Dinitrophenol-C, by Henry Kamin and P. Handler; Reprinted from Federation Proceedings, vol. 17, No. 1, March, 1958, March, 1958
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844. Kinetics of Ammonia Metabolism in vivo, by George D. duda and Philip Handler; Reprinted from Federation Proceedings, vol. 17, No. 1, March, 1958, March, 1958
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1103. Enzymatic Oxidation of Sulfite, by Robert M. MacLeod, Walter Farkas, Irwin Fridovich and Philip Handler; Reprinted from Federation Proceedings, vol. 18, No. 1, March, 1959, March, 1959
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Some Postoperative Reactions, by Philip Handler; Reprinted from Report of the Second Institute on Clinical Teaching, 1961, 1961
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Summarizing Remarks, by Philip Handler, From J. Cell and Comp. Physiol., V. 54, Sup. 1, Dec., pp? 259 - 260, December, 1959
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Protein as a Metabolic Fuel, by P. Handler; Reprinted from Brookhaven Symposia in Biology No. 5 (BNL 206 [C-15]), September, 1952
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Utilization of the Photosensitized Oxidation of Sulfite for Manometric Actinometry, by Irwin Fridovich and Philip Handler; Reprinted from Biochim. Bioghys Acta, vol. 35, 1959, 1959
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Major Metabolic Fuels - Brookhaven Symposia in Biology No. 5, Sept., 1952, September, 1952
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Radiation and Agine, by Philip Handler; Reprinted from Aging, 1960
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Biosynthesis of Trigonelline, by Jayant G. Joshi and Philip Handler; From The Journal of Biological Chemistry, Vol. 235, No. 10, Oct., 1960, October, 1960
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Detection of Free Radicals in Illuminated Dye Solutions, by the Initiation of Sulfite Oxidation, by Irwin Fridovich and Philip Handler; From The Journal of Biological Chemistry, Vol. 235, No. 6, June, 1960, June, 1960
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Some Postoperative Reactions Pastoperative Reactions of a Basic Scientist, by Philip Handler; Reprinted from Report of the Second Institute on Clinical Teaching (1959), 1961, 1959, 1961
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Detection of Free Radicals Generated During Enzymic Oxidations, by the Initiation of Sulfite Oxidation, by Irwin Fridovich and Philip Handler; From The Journal of Biological Chemistry, vol. 236, No. 6, June, 1961, June, 1961
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Competitive Inhibition of Enzyme Activity, by Urea, by K.V. Rajagopalan, Irwin Fridovich and Philip Handler; From The Journal of Biological Chemistry, Vol. 236, No. 4, April, 1961, April, 1961
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Biosynthesis of Diphosphopyridine Nucleotide III. Nicotinic Acid Mononucleotide Pyrophosphorylase, by John Imsande and Philip Handler; From The Journal of Biological Chemistry, Vol. 237, No. 2, Feb., 1961, February, 1961
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Mechanism of the Factitious Stimulation of Biological Oxidations, by Hypoxanthine, by Robert M. MacLeod, Irwin Fridovich and Philip Handler; From The Journal of Biological Chemistry, Vol. 236, No. 6, June, 1961, June, 1961
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Contributions of Biochemical Research to Progress in Medicine, by Philip Handler, Ph.D., Reprinted from The Journal of The American Medical Association, Sept. 23, 1961, vol. 177, pp. 840 - 849, September 23, 1961
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Introduction, by Philip Handler; Reprinted from Federation Proceedings, vol. 20, No. 2, July, Supp. 8, 1961, 1961
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Biochemical Considerations of Relationships Between Effects of Time and of Radiation on Living Systems, by Philip Handler; Reprinted from Federation Proceedings, Vol. 20, No. 2, Pt. 2, July, Supp. 8, 1961, 1961
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The Bio-Medical Research Training Program of Duke University, by Philip Handler and James B. Wyngaarden; Reprinted from The Journal of Medical Education, Vol. 36, No. 11, Nov., 1961, November, 1961
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Purification and Properties of Hepatic Sulfite Oxidase, by Robert M. MacLeod, Walter Farkas, Irwin Fridovich and Philip Handler; From The Journal of Biological Chemistry, Vol. 236, No. 6, June, 1961, June, 1961
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Science and Government - Opportunities and Conflicts, by Philip Handler; From The Graduate Journal, Vol. VIII, No. 1, 1968, 1968
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The Young Scientist - Hour of Decision Address, by Philip Handler; Presented at the Awards Banquet of the Science Talent Search for- the Westinghouse Science Scholarships and Awards, Sheraton-Park Hotel, Washington, DC, March 3, 1969, March 3, 1969
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The Oxidative Demethylation of Sarcosine to Glycine, by Philip Handler, Mary L.C. Bernheim, and J. Raymond Klein; From The Journal of Biological Chemistry, Vol. 138, No. 1, March, 1941, March, 1941
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Synthesis of Nicotinic Acid, by the Chick Embryo, by WLJ. Dann and Philip Handler; From The Journal of Biological Chemistry, vol. 140, No. 3, Sept., 1941, September, 1941
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The Oxidation in vitro of N-Methylamino Acids, by Kidney and Liver, by Philip Handler, Frederick Bernheim, and J. Raymond Klein; From The Journal of Biological Chemistry, Vol. 138, No. 1, March, 1941, March, 1941
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Specificity of the d'Amino Acid Oxidase, by J. Raymond Klein and Philip Handler; From The Journal of Biological Chemistry, Vol. 139, No. 1, May, 1941, May, 1941
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Azlactones III. Acylation of ,Amino Acids in Pyridine, by Herbert E. Carter, Philip Handler, and Carl M. Stevens; From The Journal of Biological Chemistry, Vol. 138, No. 2, April, 1941, April, 1941
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The Nicotinic Acid and Coenzyme Content of Animal Tissues, by Philip Handler and W.J. Dann; From The Journal of Biological Chemistry, Vol. 140, No. 3, Sept., 1941, September, 1941
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The Quantitative Estimation of Nicotinic Acid in Animal Tissues, by W.J. Dann and Philip Handler; From The Journal of Biological Chemistry, Vol. 140, No. 1, July, 1941, July, 1941
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The Effects of various Inhaibiots of Carbohydrate Metabolism in Vivo, by Philip Handler; From The Journal of Biological Chemistry, vol. 161, No. 1, Nov., 1945, November, 1945
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The Robert Welch Foundation Research Bulletin - Academic Science and the Federal Government, by Philip Handler; Bulletin No. 22, May, 1968, Houston, Texas, May, 1968
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Human Protein Requirements and Their Fulfillment in Practice; Proceedings of a Conference in Princeton, United States (1955); Sponsored Jointly, by the Food and Agriculture Organization of the United Nations (FAO), World Health Organization (WHO), Josiah Macy, Jr. Foundation, New York, 1955
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Major Metabolic Fuels; Associated Universities, Inc. Under Contract with the United States Atomic Energy Commission Brookhaven Symposia in Biology No. 5, Sept., 1952, September, 1952
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Biochimica et Biophysica Acta - Suggestions and Instructions to Authors; Revised (1965) Edition; Elsevier Publishing Company, Ameterdam, 1965, 1965
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Alumni of the Duke University School of Medicine, Start - 1956, 1956
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Stratoscope: Princeton University High Altitude Balloon Astronomy Program, undated
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What Do Idaho Teenagers Eat?; Idaho Agricultural Extension Service, Bulletin 272, March, 1957, March, 1957
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Nutritional Status of School Children 15 and 16 Years of Age in Three Idaho Communities, by Kathleen P. Warwick, Shirley V. Bring, and Ella Woods; University of Idaho College of Agriculture, undated
Box 9
Dietary Studies of Montana Fifteen-Year-Olds and of Montana College Freshmen, The Human Nutrition Research Branch, U.S. Dept. of Agriculture and Montana State College Agricultural Experiment Station, Boseman, Mont.; Bulletin 518, April, 1956, April, 1956
Box 9
The Nutritional value of Food Purchased in 1953, by 146 Urban Families - MSU Consumer Panel Bulletin No. 4, Michigan State University Agricultural Experiment Station Department of Foods and Nutrition, Technical Bulletin 258, July, 1956, July, 1956
Box 9
Food Habits of South Dakota Women; Home Economics Department, Agricultural Experiment Station, South Dakota State College, Brookings, Bulletin 451, May, 1955, May, 1955
Box 9

4. Associations, 1932-1969

American Board of Clinical Chemistry, Inc., 1951-1958
Box 10
American Chemical Society, 1961
Box 10
ACS, 1961
Box 10
American College Physicians, 1953-1954
Box 10
American Heart Association, Inc., 1958-1960
Box 10
AIBS - NIH - AEC Ageing Panel, 1958-1963
Box 10
American Institute of Biological Sciences, 1958
Box 10
AIBS - BSCS Memos, 1958-1963
Box 10
AIBS - BSCS Memos, 1960-1962
Box 10
AIBS - BSCS, 1952-1959
Box 10
American Institute of Nutrition, 1960-1962
Box 10
American Med. Assoc., 1959
Box 10
American Sterilizer Co., 1959-1960
Box 10
American Association of Medical Colleges Institute on Clinical Teaching, 1951-1961
Box 10
Animal Tower, 1955-1957
Box 10
Annual Review of Biochemistry, 1961-1962
Box 10
Arden Instruments, 1952-1957
Box 10
Armour and Company, 1947-1952
Box 10
A.S. Aloe Company, 1948-1963
Box 10
A.E.C. - Direct Contract, undated
Box 10
Association of American Medical Colleges - File I, undated
Box 11
Association of American Medical Colleges - File II, undated
Box 11
AAMC - File III, 1949-1957
Box 11
AEC - Consultant, undated
Box 11
AEC - Radioisotope Application Forms, undated
Box 11
AEC Equipment Grant, undated
Box 11
Calcium-45 Applications, undated
Box 11
Carbon-14 Applications, undated
Box 11
Copper 64 Applications Correspondence, undated
Box 11
Fe 55, undated
Box 11
Iodine-131 Applications, undated
Box 11
Phosphorus-32 Applications, undated
Box 11
Potassium-42 Applications, undated
Box 11
Sulfur 35 Applications, undated
Box 11
AEC Radioisotope Applications - Isotope Laboratory, undated
Box 11
AEC Application for Radioisotope research Support, undated
Box 11
AEC - Fellows, undated
Box 11
AEC - Course Correspondence, undated
Box 11
AEC - General Correspondence Miscellaneous, undated
Box 11
AEC - Program Correspondence, undated
Box 11
Atomic energy of Canada Limited, 1959-1960
Box 11
ASBC Council, 1932-1969
Box 12

5. Laboratory and Classroom Materials, 1932-1969

Med Students' Re-exam, undated
Box 12
Laboratory Exam III, undated
Box 12
Laboratory Exam II, undated
Box 12
Laboratory Exam I, undated
Box 12
Biochemistry 304 - Proteins and Enzymes, undated
Box 12
Biochemistry 308 - Metabolism, undated
Box 12
Courses - General, 1968-1969
Box 12
Course - Biochem of Disease, undated
Box 12
Airline Guide, 1932-1963
Box 12
Medical Students - Correspondence, undated
Box 12
Med. Student Exams, 1951, 1952-1955
Box 12
Biochemistry Lecture - Lab Schedule (1st Year Med. Students), undated
Box 12
PH - Personal Current Activities, undated
Box 12
PH - Personal CVS, undated
Box 12
PH - Personal CVs, undated
Box 12
PH - Personal CVs, undated
Box 12

6. Unprocessed Materials, 1939-1980

Pubilcations of Philip Handler, 1939-1956
Box 13
Pubilcations of Philip Handler, 1957-1966
Box 13
Pubilcations of Philip Handler, 1967-1969
Box 13
Pubilcations of Philip Handler, 1970-1971
Box 13
Pubilcations of Philip Handler, 1980, undated
Box 13

Biographical Note

Philip Handler was born in New York, N.Y. in 1917. He received degrees from the College City of New York (B.S., 1936); and University of Illinois (Ph.D., 1939). Dr. Handler joined Duke University as an instructor of biochemistry in 1939. He held many positions at Duke University: instructor (1939-1940), associate professor (1940-1941), assistant professor of physiology (1941-1944), associate professor of biochemistry and nutrition (1944-1949), professor of biochemistry (1949-1969). He also served as chair of the Department of Biochemistry from 1950-1969 and was named a James B. Duke Professor of Biochemistry in 1961. In 1964 Dr. Handler was elected to membership in the National Academy of Sciences. Five years later, he was selected to be the society's eighteenth president. He served two consecutive six-year terms from 1969 to 1981. As a biochemist, Dr. Handler published more than 200 papers in important professional journals and was the coauthor of the widely used textbook. One of his first major research efforts was on the underlying problems that cause pellagra. He also made other contributions to understanding the mechanisms by which enzyme proteins carry out their catalytic functions in metabolism. Handler was also on the editorial board of periodicals including,,, and. Dr. Handler was the recipient of numerous awards and twenty-eight honorary doctorate degrees. Among many honors, he was the Annual Orator of the Harvey Cushing Society and of the Welch Foundation, Sigma Xi National Lecturer, and delivered memorial lectures at many scientific institutions in the United States and abroad. He served on the boards and visiting committees of more than a dozen scientific institutions and was decorated by the governments of Austria, Belgium, and Poland. Handler also served as a consultant to the United States Veteran's Administration, Mead Johnson and Company, Squibb, Inc., and Continental Baking Company. Dr. Handler's major activities in science and public policy began in 1951, when he accepted the first in a series of government advisory appointments. He served for twelve years on the National Science Board and was member of the President's Science Advisory Committee under two presidents. In 1981, he was awarded the National Medal of Science. A citation signed by President Reagan honored him Dr. Handler married Lucille P. Marcus in 1939. Together they had two children. Dr. Handler died on December 29, 1981.

Subject Headings

Preferred Citation

[Identification of item], Philip Handler papers, Duke University Medical Center Archives.

Acquisitions Information

Gift; 1985.

Processing Information

Processed by Archives staff, June 2005 Encoded by Emily Glenn, June 2005