Collection Finding Aid

Comprehensive Cancer Center Pharmaceutical Research Services Records

Collection Number: AR.0081

This is a finding aid. It is a description of archival material held in the Duke Medical Center Archives in Durham, N.C. Unless otherwise noted, the materials described below are physically available in our reading room, and not digitally available through the World Wide Web. See the FAQ section for more information.


Collection Overview expand/collapseExpand/collapse

Estimated Extent: 23.00 linear feet
Abstract: Pharmaceutical Research Services, part of Duke Comprehensive Cancer Center, consists of an Investigational Chemotherapy Service and a Cancer Clinical Pharmacology Laboratory and provides a broad range of services to support the conduct of clinical hematology/oncology research. Types of materials include laboratory notebooks, data, correspondence, clnical trials materials, and research materials from both academic and clinical research. Materials were created by academic and clinical research staff members of the following departments: Dept. of Medicine, Dept. of Pathology, and Dept. of Pharmacology and Cancer Biology.
Creator: Duke University. Comprehensive Cancer Center. Pharmaceutical Research Services.
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Information for Users expand/collapseExpand/collapse

Access Restrictions
This collection contains personal health information. Contact the Archivist for information about access. Contains University Administrative records. These include records of the officers of the University, as defined in the Bylaws, the deans of schools and colleges, and departments, institutes, and other offices as designated by the President. For a period of twenty-five years from the origin of the material, permission in writing from the director of the office of record and the University Archivist is required for use. After twenty-five years, records that have been processed may be consulted with the permission of the University Archivist. (Issued by the Office of the Chancellor, December 1, 1975). This collection may contain material with sensitive or confidential information that is protected under federal or state right to privacy laws and regulations, including the Health Insurance Portability and Accountability Act (HIPAA). Researchers are advised that the disclosure of certain information pertaining to identifiable individuals represented in this collection without the consent of those individuals or IRB approval may have legal ramifications (e.g., a cause of action under common law for invasion of privacy may arise if facts concerning an individual's private life are published that would be deemed highly offensive to a reasonable person) for which Duke University assumes no responsibility.
Copyright Notice
Copyright for Official University records is held by Duke University; all other copyright is retained by the authors of items in these papers, or their descendants, as stipulated by United States copyright law.
Preferred Citation
[Identification of item],Pharmaceutical Research Services records, Duke University Medical Center Archives.
Acquisitions Information
Transfer; A2005-027; 2005.
Sensitive Materials Statement
Collections may contain Medical Center Administrative records. These include records of the officers of the University, as defined in the Bylaws, the deans of schools and colleges, and departments, institutes, and other offices as designated by the President. For a period of twenty-five years from the origin of the material, permission in writing from the director of the office of record and the Medical Center Archivist is required for use. After twenty-five years, records that have been processed may be consulted with the permission of the Medical Center Archivist.
Collection may contain Records of the Board of Trustees of the Duke University Medical Center. These include minutes and supporting documentation of the Board, its Executive Committee, and standing and ad hoc committees, and reports, studies, and the like presented solely to the Board. Records which have been existence for at least fifty years are available for scholarly research with the permission of the Medical Center Archivist. Access to records which have been in existence for less than fifty years shall be granted only by special permission, in writing, of the Medical Center Board of Trustees.
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Subject Headings expand/collapseExpand/collapse

The following terms from Library of Congress Subject Headings and Medical Subject Headings suggest topics, persons, geography, etc. interspersed through the entire collection; the terms do not usually represent discrete and easily identifiable portions of the collectionsuch as folders or items.

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    Related Collections expand/collapseExpand/collapse

      Comprehensive Cancer Center records, circa 1943-2007

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    Historical Info expand/collapseExpand/collapse

    The Pharmaceutical Research Services, consisting of an Investigational Chemotherapy Service and a Cancer Clinical Pharmacology Laboratory, provides a broad range of services to support the conduct of clinical hematology/oncology research. The Investigational Chemotherapy Service, primarily located in the Morris Clinical Cancer Building, is available to all Cancer Center investigators for the purpose of maintaining drug accountability records and investigational drug inventories according to FDA and CTEP guidelines. In addition, this resource provides design consultation, professional staff education, implementation and report completion services for all clinical research studies. Adverse drug reaction reports from clinical trials are submitted to the service and evaluated to ensure compliance with regulatory agencies. The Clinical Pharmacology Lab is located in the Morris Clinical Cancer Building of Duke South Hospital. It functions as both a clinical research and clinical reference lab for cytokines and cytotoxic drugs. The lab routinely collaborates with a variety of Duke Cancer Center members in addition to functioning as a core facility for several investigators outside of Duke. The lab also provides both consultative and analytic services regarding clinical pharmacokinetic studies of anticancer compounds and recombinant proteins. As of 2005, the Pharmaceutical Research Services is under the co-directorship of Dr. David Adams and Dr. Ashley Morris.

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    Scope and Content expand/collapseExpand/collapse

    Organized into the following series: Records, 1985-2004.

    14 record storage boxes

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    Collection Contents

    Series Quick Links expand/collapseExpand/collapse

    Series: Records, 1985-2004expand/collapseExpand/collapse

    Box 1
    GCSF Biological Assays, undated
    AA Pt results, BMTP, undated
    AA Pt results, Trump - Total Pt, 1992
    AA Pt results, Trump - Urine Pt, Urine/UF Pt runs, carboplat adducts, 1991-1993
    Requisitions, 1992
    Protocol for treatment of metastatic melanoma using BCNU and CSFs, undated
    GCSF slides, undated
    Box 2
    AA Pt results, Trump - UF Pt, 1991-1992
    AA Pt results, Trump - total Pt, 1992, BMTP, 1992-1993
    Requisitions, 1991
    LMS study, phagocytes and H2O2 assays, 1990
    Summer project, Caroline Gupton, 1992
    CGH, 1995
    Box 3
    AA Pt results, BMTP, 1993
    Requisitisons, 1993
    Requisitisons, 1995
    Endogenous factor assays, undated
    GMCSF, 1992
    Freezer (data), circa, 1990
    GCSF EIA assays, 1990
    Erythhroprotein assay developemnt, undated
    Box 4
    GMCSF studies, undated
    IL - 1, 1990
    Diagnostic Immunology and Syphilis Serology inspection manual, 1992
    IL - 3 patients, 1992
    Requisitions, 1994
    TNF alpha, 1990
    GMCSF ELISA, 1990
    Box 5
    Statistics, undated
    EIA assasys, 1991
    AA Pt results, DNA adducts, Carboplat, 1993
    Alopeda, 1994
    EIA procedures, 1992
    AA Pt results, BMTP, 1993-1994
    IL - 1, 1991
    Box 6
    Procedures, 1990
    Molecular Devices Corporation, undated
    Participant dose data, 1985-1989
    CTX data for 8782 study, 1991
    Box 7
    Pediatrics CNS: Carboplatin MTSE, 1995-1996
    Pediatrics CNS 14, undated
    ABT-538 Ritonavir investigator brochure, undated
    Correspondence and publications, 1997-1999
    Box 8
    ICAM, M - Z, undated
    Posters, CSFs and Endogenous Cytokines I, undated
    ICAM, A - L, undated
    CNS 14, undated
    Loose files, undated
    Box 9
    Investigators meeting, protocols RC749J101-00 and RC749J102-00, 1999
    Banyu Phase I Compound J107088, multiple dose study, 1999
    Banyu Phase I Compound J107088, multiple dose study, clinical sample tracking log book, 1999
    Banyu Phase I Compound J107088, single dose study, clinical sample tracking log book, no. 1-12, 1999
    Banyu Phase I Compound J107088, single dose study, clinical sample tracking log book, no. 13-29, 1999
    Box 10
    Banyu J107088 studies, HPLC (plasma) use and maintenance log, undated
    Banyu J107088 valudation study, book 1, undated
    Banyu J107088 valudation study, book 1, urine, undated
    Banyu loose files, undated
    Banyu J107088 plasma samples, book 1, undated
    Banyu J107088 urine samples, book 1, undated
    Box 11
    Banyu J107088 plasma Valid relation study chromotograms, undated
    Banyu J107088 urine files, undated
    Banyu J107088 studies, urine files, undated
    LPAM standard curve, 2002
    Melphan perfusion study, undated
    Box 12
    LPAM standard curve, 2002
    Melphan perfusion study, undated
    Lung study, 9531, undated
    MGSF sample collection, 951002, undated
    Thalidomide study, undated
    Doxil hyperthermia study, undated
    ABX-EG-9901, undated
    OCT-43IL - 1b, endogenous cytokines, undated
    Mouthwash, ASH, 1993
    Cartee thesis, 1993
    Box 13
    GM-CSF mouthwash study, undated
    Modlin, 1993
    GM-CSF mouthwash study, undated
    Cyclophosphamide GC/MS, results for Johns Hopkins samples, undated
    Pediatric CNS: Carboplatin MTSE, undated
    Box 14
    EPO, 1993-1995
    Pediatric CNS 14 records, book 2, undated
    Pediatric CNS: Carboplatin MTSE, undated
    Tetraplatin I, undated
    Box 15
    Cyclophosphamide, BCNU, Research Data (3.5 & 5.25 disks), pre 2001

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